Bioinformatics and Biology Essentials for Librarians: Materials

Listed below are the external course materials used in the Bioinformatics and Biology Essentials for Librarians course (see link at bottom of page). This list does not include internal course content, quizzes, discussions, optional activities, or administrative information and communications.
Title Date Runtime Format
How is DNA turned into protein? The Central Dogma of Molecular Biology A reading describing how DNA is turned into protein, from Your Genome. Jan. 15, 2016 N/A HTML / Page
How Genes Work A description of DNA structure and function from The New Genetics, National Institute of General Medicine Sciences, U.S. National Institutes of Health. 2010 April. NIH Publication No. 10-662. April 1, 2010 N/A PDF / Document
DNA Replication This 3D animation shows you how DNA is copied in a cell. It shows how both strands of the DNA helix are unzipped and copied to produce two identical DNA molecules. June 26, 2015 4 min(s) MP4 Video / YouTube Video
From DNA to protein - 3D This 3D animation shows how proteins are made in the cell from the information in the DNA code. From yourgenome.org. Jan. 17, 2015 3 min(s) MP4 Video / YouTube Video
Overview of Transcription Khan Academy's overview of DNA transcription to RNA. Jan. 1, 2016 N/A HTML / Page
Transcribe and Translate a Gene An interactive tutorial on gene transcription and translation, from the Learn.Genetics Genetic Science Learning Center. Jan. 1, 2015 N/A HTML / Tutorial
Anatomy of a Gene A page describing aspects of genes, from Learn.Genetics Genetic Science Learning Center. Jan. 1, 2015 N/A HTML / Page
Talking Glossary of Genomic and Genetic Terms The glossary features nearly 250 terms explained in an easy-to-understand way by leading scientists and professionals at the National Human Genome Research Institute. Jan. 1, 2023 N/A HTML / Page
Title Date Runtime Format
Sample GenBank Record This page presents an annotated sample GenBank record (accession number U49845) in its GenBank Flat File format. Jan. 12, 2021 N/A HTML / Page
AMIA Board white paper: definition of biomedical informatics and specification of core competencies for graduate education in the discipline The core competencies for biomedical informatics, from the American Medical Informatics Association. Nov. 1, 2012 N/A HTML / Page
Title Date Runtime Format
Strawberry DNA Extraction, from the NIH National Human Genome Research Institute. With only a few household items, you can extract DNA from strawberries just about anywhere! Extracting DNA from strawberries is super easy, allowing you to learn about genomics. Join NHGRI Director Eric Green and social media specialist Jenny Montooth as they show you step-by-step how to extract DNA from strawberries using materials available in your kitchen! April 7, 2023 11 min(s) MP4 Video / YouTube Video
Polymerase chain reaction (PCR) | Biomolecules | MCAT | Khan Academy Video introduction to PCR (polymerase chain reaction) from Khan Academy. June 2, 2016 10 min(s) MP4 Video / YouTube Video
Polymerase chain reaction (PCR), from Khan Academy A page describing polymerase chain reaction, a technique used to amplify, or make many copies of, a specific target region of DNA, from Khan Academy. Jan. 1, 2016 N/A HTML / Page
Gel electrophoresis | Biomolecules | MCAT | Khan Academy Introduction to gel electrophoresis. How it's used to separate DNA fragments or other macromolecules. June 1, 2016 11 min(s) MP4 Video / YouTube Video
Gel electrophoresis A page describing gel electrophoresis, a technique used to separate DNA fragments and other macromolecules by size and charge, from Khan Academy. Jan. 1, 2016 N/A HTML / Page
Sanger Sequencing A video describing the DNA sequencing method developed by Fred Sanger, which forms the basis of automated "cycle" sequencing reactions today. Originally created for DNA Interactive. Jan. 1, 2010 1 min(s) MP4 Video / YouTube Video
Next Generation Sequencing (Illumina) - An Introduction Animated video on how the Next Gen Seq machines of ILLUMINA work April 23, 2020 5 min(s) MP4 Video / YouTube Video
Transcriptome Fact Sheet A transcriptome is a collection of all the gene readouts present in a cell. This fact sheet from the National Human Genome Research Institute explains. Aug. 17, 2020 N/A HTML / Page
RNA Sequencing Animation A video animation of RNA sequencing, from Viologia Animations. Feb. 4, 2022 4 min(s) MP4 Video / YouTube Video
Title Date Runtime Format
NCBI Taxonomy In this video, Peter Cooper from NCBI defines taxonomy and demonstrates the NCBI Taxonomy database. Jan. 24, 2024 31 min(s) MP4 Video / YouTube Video
NCBI Taxonomy: An NLM Navigator This interactive tutorial guides you through using the NCBI Taxonomy browser to identify species and find related sequence and other information in the NCBI molecular biology databases. Nov. 8, 2023 15 min(s) HTML / NLM Navigator
Title Date Runtime Format
NCBI Nucleotide Part 1 of 12: Biology Review In this video, Bonnie Maidak from NCBI provides a quick review of biology concepts needed to understand the NCBI Nucleotide database. July 18, 2024 5 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 2 of 12: Database Layout In this video, Bonnie Maidak from NCBI tours the layout of the NCBI Nucleotide database. Jan. 24, 2024 2 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 3 of 12: Finding a nucleotide sequence for a gene In this video, Bonnie Maidak from NCBI demonstrates searching the Nucleotide database for a gene product. Jan. 24, 2024 3 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 4 of 12: What is in a record? In this video, Bonnie Maidak from NCBI highlights the features of a record in the NCBI Nucleotide database. Jan. 24, 2024 5 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 5 of 12: Refining a search In this video, Bonnie Maidak from NCBI uses [title] and [organism] searches to refine her search for APRT sequences in the NCBI Nucleotide database. Jan. 24, 2024 5 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 6 of 12: Record types In this video, Bonnie Maidak from NCBI explains the different types of records in the Nucleotide database. Jan. 24, 2024 5 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 7 of 12: Downloading sequence data In this video, Bonnie Maidak from NCBI demonstrates how to download data from the Nucleotide database. Jan. 24, 2024 1 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 8 of 12: A shortcut to finding RefSeq records In this video, Bonnie Maidak from NCBI provides a shortcut for finding RefSeq records in the NCBI Nucleotide database. Jan. 24, 2024 1 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 9 of 12: Finding Chromosome Records In this video, you will learn how to find chromosome records in the NCBI Nucleotide database. Aug. 21, 2024 3 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 10 of 12: Inside a Chromosome Record In this video you will learn what information you can find on a chromosome record in the Nucleotide database. Aug. 21, 2024 3 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 11 of 12: The Graphical Display In this video, you will learn how to navigate to the graphical display of a chromosome, narrow down to the area of a specific gene, and select tracks to display. Aug. 21, 2024 4 min(s) MP4 Video / YouTube Video
NCBI Nucleotide Part 12 of 12: Assembly Records In this video you will learn how to find assembly records, use them to find the sequence data that comprise the assembly and download data, starting in the NCBI Nucleotide database. Aug. 21, 2024 7 min(s) MP4 Video / YouTube Video
NCBI Nucleotide: An NLM Navigator This interactive tutorial provides a tour of the NCBI Nucleotide database, a database of nucleic acid sequences from GenBank and other DNA and RNA sequence repositories. Oct. 20, 2023 15 min(s) HTML / NLM Navigator
Title Date Runtime Format
Using NCBI BLAST In this video, Peter Cooper from NCBI describes and demonstrates the NCBI BLAST service. Jan. 24, 2024 50 min(s) MP4 Video / YouTube Video
NCBI BLAST: Identifying Sequences: An NLM Navigator This interactive tutorial walks you through your first BLAST to identify the source of a DNA or RNA sequence. Oct. 20, 2023 15 min(s) HTML / NLM Navigator
NCBI BLAST: Comparing Sequences: An NLM Navigator This interactive tutorial walks you through a simply BLAST to compare sequences. Allow pop-ups to use this Navigator. Nov. 15, 2023 10 min(s) HTML / NLM Navigator

Gene Annotation and NCBI

Title Date Runtime Format
The Genome Reference Consortium Sept. 9, 2024 N/A HTML / Page
Genome assembly GRCh38.p14 Sept. 9, 2024 N/A HTML / Page
The double helix structure of DNA Oct. 9, 2024 N/A HTML / Page
Gene annotation in Ensembl Sept. 9, 2024 N/A HTML / Page

Part 1: About the NCBI Gene Database

Title Date Runtime Format
NCBI Gene Part 1 of 5: About the NCBI Gene Database Jan. 25, 2024 3 min(s) MP4 Video / YouTube Video

Part 2: Find the Gene in the Genome

Title Date Runtime Format
NCBI Gene Part 2 of 5: Find the Gene in the Genome Jan. 25, 2024 7 min(s) MP4 Video / YouTube Video
NCBI Gene: Finding the Gene in the Genome: An NLM Navigator Aug. 27, 2024 10 min(s) HTML / NLM Navigator

Part 3: Reference Sequences

Title Date Runtime Format
NCBI Gene Part 3 of 5: Reference Sequences Jan. 25, 2024 15 min(s) MP4 Video / YouTube Video
NCBI Gene: Finding the Reference Sequences: An NLM Navigator Sept. 27, 2024 15 min(s) HTML / NLM Navigator

Part 4: Find Gene Expression Data

Title Date Runtime Format
NCBI Gene Part 4 of 5: Find Gene Expression Data Jan. 25, 2024 5 min(s) MP4 Video / YouTube Video
NCBI Gene: Finding Gene Expression Data: An NLM Navigator Aug. 27, 2024 20 min(s) HTML / NLM Navigator

Part 5: Gene Variants and Associations with Disease

Title Date Runtime Format
NCBI Gene Part 5 of 5: Gene Variants and Associations with Disease Jan. 25, 2024 9 min(s) MP4 Video / YouTube Video
NCBI Gene: Finding and Exploring Variations: An NLM Navigator Sept. 27, 2024 20 min(s) HTML / NLM Navigator
IGSR: The International Genome Sample Resource Oct. 28, 2024 N/A HTML / Site
Title Date Runtime Format
What is a Protein? Video describing proteins, from the Protein DataBank (PDB). Nov. 20, 2017 7 min(s) MP4 Video / YouTube Video
NCBI Protein Biology Basics In this video, Kate Majewski from the National Library of Medicine explains some protein biology basics needed to understand the NCBI Protein database. Jan. 24, 2024 8 min(s) MP4 Video / YouTube Video
Title Date Runtime Format
NCBI Protein and Structure Part 1 of 8: NCBI Protein Database Layout In this video , Kate Majewski from the U.S. National Library of Medicine gives a tour of the NCBI Protein database web pages. Jan. 24, 2024 5 min(s) MP4 Video / YouTube Video
NCBI Protein and Structure Part 2 of 8: Searching the Protein Database In this video , Peter Cooper from the U.S. National Library of Medicine explains how to search the protein database. Jan. 24, 2024 8 min(s) MP4 Video / YouTube Video
NCBI Protein and Structure Part 3 of 8: Protein Sequence Records In this video, Peter Cooper from the U.S. National Library of Medicine shows how to view protein sequence records in the NCBI Protein database. Jan. 24, 2024 8 min(s) MP4 Video / YouTube Video
NCBI Protein and Structure Part 4 of 8: Identical Sequences In this video, Peter Cooper from the U.S. National Library of Medicine shows how to use the identical proteins tool in the NCBI Protein database. Jan. 24, 2024 11 min(s) MP4 Video / YouTube Video
NCBI Protein and Structure Part 5 of 8: Finding Structures In this video , Peter Cooper from NCBI uses the Protein database to find structures for adenosine deaminase. He starts with the search for: human[orgn] AND adenosine deaminase[ti]]. Jan. 24, 2024 8 min(s) MP4 Video / Video Tutorial
NCBI Protein and Structure Part 6 of 8: Viewing a Structure with iCn3D In this video, Peter Cooper from NCBI demonstrates how to use iCn3D to view a structure. Feb. 9, 2024 9 min(s) MP4 Video / YouTube Video
NCBI Protein and Structure Part 7 of 8: Using PubChem to Find Structures with Specific Molecules In this video, Peter Cooper from NCBI demonstrates how to find structures that contain a particular molecule bound to it using the PubChem database. Jan. 24, 2024 4 min(s) MP4 Video / YouTube Video
NCBI Protein and Structure Part 8 of 8: Finding Structures with Specific Biological Features In this video, Peter Cooper from NCBI demonstrates how to find a structure with specific biological features using the NCBI Structure database. Jan. 24, 2024 8 min(s) MP4 Video / YouTube Video
NCBI Protein: Simple Search and Record Structure: An NLM Navigator This interactive tutorial guides you through searching for proteins in the NCBI Protein database and exploring the information found there. Oct. 20, 2023 15 min(s) HTML / NLM Navigator
NCBI Structures: Viewing a Protein Structure: An NLM Navigator This interactive tutorial guides you through finding a protein in the NCBI Protein Database and viewing it in the NCBI Structure database. Oct. 20, 2023 10 min(s) HTML / NLM Navigator
NCBI Structures: Find Protein Structures with Specific Components: An NLM Navigator This interactive tutorial guides you how to use PubChem to find structures with specific components in the NCBI Structure database. Oct. 20, 2023 10 min(s) HTML / NLM Navigator
Title Date Runtime Format
NCBI Clinical Databases: Biology Review This video reviews some biology basics important to using NCBI's clinical databases. Jan. 24, 2024 7 min(s) MP4 Video / YouTube Video
NCBI Clinical Databases: Overview This video provides an overview of three NCBI clinical databases: MedGen, ClinVar and Genetic Testing Registry (GTR). Jan. 24, 2024 3 min(s) MP4 Video / YouTube Video

MedGen

Title Date Runtime Format
MedGen Jan. 25, 2024 6 min(s) MP4 Video / YouTube Video
NCBI MedGen: An NLM Navigator Aug. 27, 2024 10 min(s) HTML / NLM Navigator

ClinVar: Clinical Variation

Title Date Runtime Format
ClinVar Feb. 7, 2024 10 min(s) MP4 Video / YouTube Video
NCBI ClinVar: Clinical Variation: An NLM Navigator Aug. 27, 2024 10 min(s) HTML / NLM Navigator

Genetic Testing Registry (GTR)

Title Date Runtime Format
Genetic Testing Registry Jan. 25, 2024 3 min(s) MP4 Video / YouTube Video
NCBI Genetic Testing Registry (GTR): Finding Genetic Tests: An NLM Navigator Sept. 27, 2024 5 min(s) HTML / NLM Navigator

Patient Data Confidentiality and Privacy

Data Reporting to Patients

Data Analysis: Motivations and Challenges to Reproducibility and Data Sharing in Biomedicine

Title Date Runtime Format
Why Data Sharing & Reuse Are Hard To Do? Sept. 18, 2024 62 min(s) MP4 Video / YouTube Video

See Also